Κωνσταντίνος Πίτσιος
ΠΙΤΣΙΟΣ ΚΩΝΣΤΑΝΤΙΝΟΣ
-
...
ΕΙΔΙΚΟ ΕΚΠΑΙΔΕΥΤΙΚΟ ΠΡΟΣΩΠΙΚΟ
Ιατρική Σχολή
Σιακόλειο Εκπαιδευτικό Κέντρο Κλινικής Ιατρικής
Παλαιός Δρόμος Λευκωσίας Λεμεσού Αρ. 215/6
124
22895226
22895396
https://www.researchgate.net/profile/Constantinos_Pitsios

Προσωπικό Προφίλ

ΣΠΟΥΔΕΣ-ΕΚΠΑΙΔΕΥΣΗ
Απόφοιτος της Ιατροχειρουργικής Σχολής ‘La Sapienza’ Ρώμης, Ιταλίας, (1986-1992)  
Στρατιωτική θητεία στην Πολεμική Αεροπορία (1993-1994), κατά τη διάρκεια της οποίας εκπαίδευση στην Καρδιολογική  Κλινική και ειδικότητα στην Πνευμονολογική Κλινική του 251 Γενικού Νοσοκομείου Αεροπορίας.
Ειδικότητα Παιδιατρικής, ως προαπαιτούμενη για την Αλλεργιολογία, στην Β΄ Παιδιατρική Κλινική του Γενικού Νοσοκομείου Παίδων Πεντέλης (1997- 1999).
Ειδικότητα Αλλεργιολογίας, στο Αλλεργιολογικό Τμήμα του Γ.Ν.Α. «Λαϊκό» (2001-2004), με επί μερους εκπαίδευση στην Δερματολογία («Ευαγγελισμός» και «Α. Συγγρός»), στις Αναπνευστικές Δοκιμασίες («Ευγενίδειο») και στο Αλλεργιολογικό Τμήμα του Ν. Π. «Αγλ. Κυριακού».
Εξειδίκευση στην τροφική αλλεργία ως ειδικευόμενος (2003) και ως επισκέπτης ιατρός (2005), στο Mount Sinai School of Medicine, Νέας Υόρκης, Η.Π.Α.
Τίτλος του Διδάκτορος Ιατρικής Σχολής του Εθνικού Καποδιστριακού Πανεπιστημίου Αθηνών (2008), για την διατριβή “Μελέτη του αντιγόνου ενεργοποίησης CD69 στα διάφορα στάδια της HIV-1 λοίμωξης. Συσχέτιση με υποπληθυσμούς Τ λεμφοκυττάρων (CD4, CD8, CD28) και λειτουργικές δοκιμασίες”.

ΕΚΠΑΙΔΕΥΤΙΚΗ ΚΑΙ ΚΛΙΝΙΚΗ EMΠΕΙΡΙΑ
Διδασκαλία Αλλεργιολογίας και Ανοσολογίας της HIV λοίμωξης, Τμήμα Ειδικότητας Παθολογικής Νοσηλευτικής, 251 Γ.Ν.Α (2005).
Επιστημονικός συνεργάτης Σχολής Διαιτολογίας-Διατροφής, Χαροκόπειο Πανεπιστήμιο Αθηνών, με διαδασκαλία στα προπτυχιακά μαθήματα «Παθοφυσιολογία ΙΙ» (2009-2015), «Διατροφή και Ανοσία» (2011)
 Διδασκαλία σε μεταπτυχιακούς φοιτητές της Σχολής Διαιτολογίας-Διατροφής, Χαροκοπείου Πανεπιστημίου, στα πλαίσια του μαθήματος «Ειδικά θέματα κλινικής διατροφής ενηλίκων» (2012-2016).
Επιβλέπων της μεταπτυχιακής διατριβής «Μελέτη της IgE-ευαισθητοποιήσης στην προφιλίνη και η κλινική της σημασία στη πρόκληση αλλεργίας», της μεταπτυχιακής φοιτήτριας Άννας Ηλιοπούλου, Χαροκόπειο Πανεπιστήμιο.
Αλλεργιολόγος σε ιδιωτικό ιατρείο και υπεύθυνος Αλλεργιολογικού Ιατρείου τ.ΤΑΞΥ και Πολυιατρείων Αθηνών ΕΟΠΥΥ (2004-2013).

ΕΠΙΣΤΗΜΟΝΙΚΗ ΔΡΑΣΤΗΡΙΟΤΗΤΑ
Μέλος του ΔΣ του Immunotherapy Interest Group της Ευρωπαϊκής Ακαδημίας Αλλεργιολογίας και Κλιν. Ανοσολογίας EAACI, (2011-2017).          Μέλος του ΔΣ του Eosinophilic Esophagitis Working Group της Ευρωπαϊκής Ακαδημίας Αλλεργιολογίας και Κλιν. Ανοσολογίας EAACI, (2017-2019).
Συντονιστής του Task Force “Contraindications in Immunotherapy” του Immunotherapy Interest Group της EAACI (2012-2014).                             Μέλος σε διάφορα Task Forces Κατευθυντηρίων Οδηγιών της Ευρωπαϊκής Ακαδημίας Αλλεργιολογίας, με αντικείμενο την Ανοσοθεραπεία και την Ηωσινοφιλική Οισοφαγίτιδα.
Ειδικός Γραμματέας της Ελληνικής Εταιρείας Αλλεργιολογίας & Κλιν. Ανοσολογίας, 2011-2014.

ΕΚΔΟΤΙΚΟ ΕΡΓΟ
Συντακτική επιτροπή περιοδικού «Ελληνική Αλλεργιολογία και Κλινική Ανοσολογία» (2008-σήμερα) και υπεύθυνος ύλης του περιοδικού (2010-σήμερα).
Κριτής σε αγγλόφωνα περιοδικά (Annals Allergy Clinical Immunology, Clinical Translational Allergy, Pediatric Allergy & Immunology, Clinical and Molecular Allergy, Journal of Molecular Evolution, Journal of Medical Case Reports).

 

Ως συντονιστής του Task Force “Contraindications in Immunotherapy” του Immunotherapy Interest Group της Ευρωπαϊκής Ακαδημίας Αλλεργιολογίας EAACI, υπεύθυνος για την δημοσίευση των Κατευθυντήριων Οδηγιών Ανοσοθεραπείας που ήδη αποτελούν σημαντική παρακαταθήκη της ειδικότητας. Υπό δημοσίευση είναι μελέτη που αφορά στην γνώμη των ειδικών επί των αντενδείξεων ανοσοθεραπείας.

Συμμετοχή στην εκπόνιση Κατευθυντήριων Οδηγιών Ανοσοθεραπείας της Ακαδημίας EAACI, και συγκεκριμένα στις ομάδες για την α) Αλλεργική ρινίτιδα και την β) Αλλεργία σε δηλητήριο Υμενοπτέρων. Ήδη υπάρχουν αρχικές δημοσιεύσεις, ενώ τον Ιούνιο 2016 πρόκειται να ολοκληρωθούν οι Οδηγίες και να εκτυπωθεί σχετικό σύγγραμα.

Ειδικό ενδιαφέρον σε τροφικά αλλεργιογόνα και συγκεκριμένα στην προφιλίνη. Έχει ολοκληρωθεί μελέτη του επιπολασμού της ευαισθησίας Ελληνικού πληθυσμού στην προφιλίνη. Έχει γίνει μελέτη του Αλλεργιοκού συνδρόμου στοματοφάρυγγα και η συμβολή της προφιλίνης σε αυτό και τα αποτελέσματα έχουν ανακοινωθεί σε διεθνή συνέδρια. Η συγγραφή σχετικού άρθρου βρίσκεται σε φάση ανάλυσης δεδομένων. Ακόμη πρόκειται να μελετηθεί η ύπαρξη προφιλίνης σε αλλεργιογόνες γύρεις της Μεσογείου και σε φρούτα, με τη μέθοδο SDS-PAGE, από το Κέντρο Ερευνών Μοριακής Ιατρικής, Πανεπιστημίου Κύπρου.

1. Pitsios C, Vithoulka A, Roumana A, Kompoti E, Kontou-Fili K. Multiple Physical Urticarias: Report of Three Cases and Review of the Literature. Allergy and Asthma Proceedings, 2003; Vol 24, 5:313-317.

2. Pitsios C, Papadopoulos D, Kompoti E, Manoussakis E, Garris V, Petalas K, Tassios I, Baibas N, Kontou-Fili K, Saxoni-Papageorgiou P, Papadopoulos NG. Efficacy and safety of mometasone furoate vs nedocromil sodium as prophylactic treatment for moderate/severe seasonal allergic rhinitis. Annals of Allergy, Asthma and Immunology, 2006; 96, 5:673-678.

3. Vythoulka A, Pitsios C, Kompoti E. Allergic reactions due to mizolastine. Annals of Allergy, Asthma and Immunology, 2006; 97, 2:262-263.

4. Stratopoulos C, Pitsios C, Valenti P, Anaglostopoulos G, Kotronis E. Medical Image. Deep vein thrombosis due to absence of inferior vena cava. N J Med J, 2006; 119:U2288.

5. Pitsios C, Chliva C, Mikos N, Kompoti E, Nowak-Wegrzyn A, Kontou-Fili K. Bee pollen sensitivity in airborne pollen allergic individuals. Annals of Allergy, Asthma and Immunology, 2006; 97:703-706.

6. Vartholomaios S, Pitsios C, Mikos N, Kompoti E, Kouridakis S. Allergy to Basil; a Lamiaceae herb. J Inv Allergy Clin Immunol, 2007; 17: 345-349.

7. Pitsios C, Dimitrakopoulou A, Tsalimalma K, Kordossis T, Choremi-Papadopoulou H. Expression of CD69 on T-cell subsets in HIV-1 disease. Scand J Clin Lab Invest, 2008; 68: 233-241.

8. Stefanaki E, Pitsios C Occupational dermatitis due to carnation. Contact Dermat, 2008; 58: 119-120.

9. Pitsios C, Ergazakis M, Vartholomaios S, Kompoti E, Kontou-Fili K. Honey hypersensitivity in two atopic patients.  Allergy Hypersensitivity Asthma, 2008: 17-20.

10. Roumana A, Pitsios C, Vartholomaios S, Kompoti E, Kontou-Fili K. The safety of initiating Hymenoptera immunotherapy at 1 microg of venom extract. J Allergy Clin Immunol, 2009; 124:379-81.

11. Pitsios C, Dimitriou A, Stefanaki EC, Kontou-Fili K. Anaphylaxis during skin testing with food allergens in children. Eur J Pediatr, 2009; 169: 613-615.

12. Pitsios C, Stefanaki EC, Helbling A. Type IV delayed-type hypersensitivity of the respiratory tract due to budesonide use: report of two cases and a literature review. Prim Care Respir J, 2010; 19:185-188.

13. Pitsios C, Dimitriou A, Kontou-Fili K. Allergic reactions during allergy skin testing with food allergens. Εur Ann Allergy Clin Immunol, 2009; 41: 126-8.

14. Pitsios C Generalized allergic reactions during skin testing. Pediatr Allergy Immunol, 2010; 21: 557.

15. Pitsios C, Del Giacco S, Grigoreas C. Is free running screening test still useful? West Indian Med J, 2010; 59: 287-290.

16. Syrigou E, Pitsios C, Panagiotou I, Chouliaras G, Kitsiou S, Kanariou M, Roma-Giannikou E. Food allergy-related paediatric constipation: the usefulness of atopy patch test. Eur J Pediatr, 2011; 170: 1173-1178.

17. Papadopoulos NG, Agache I, Bavbek S, Bilo BM, Braido F, Cardona V, Custovic A, Demonchy J, Demoly P, Eigenmann P, Gayraud J, Grattan C, Heffler E, Hellings PW, Jutel M, Knol E, Lötvall J, Muraro A, Poulsen LK, Roberts G, Schmid-Grendelmeier P, Skevaki C, Triggiani M, Vanree R, Werfel T, Flood B, Palkonen S, Savli R, Allegri P, Annesi-Maesano I, Annunziato F, Antolin-Amerigo D, Apfelbacher C, Blanca M, Bogacka E, Bonadonna P, Bonini M, Boyman O, Brockow K, Burney P, Buters J, Butiene I, Calderon M, Cardell LO, Caubet JC, Celenk S, Cichocka-Jarosz E, Cingi C, Couto M, Dejong N, Del Giacco S, Douladiris N, Fassio F, Fauquert JL, Fernandez J, Rivas MF, Ferrer M, Flohr C, Gardner J, Genuneit J, Gevaert P, Groblewska A, Hamelmann E, Hoffmann HJ, Hoffmann-Sommergruber K, Hovhannisyan L, Hox V, Jahnsen FL, Kalayci O, Kalpaklioglu AF, Kleine-Tebbe J, Konstantinou G, Kurowski M, Lau S, Lauener R, Lauerma A, Logan K, Magnan A, Makowska J, Makrinioti H, Mangina P, Manole F, Mari A, Mazon A, Mills C, Mingomataj E, Niggemann B, Nilsson G, Ollert M, O'Mahony L, O'Neil S, Pala G, Papi A, Passalacqua G, Perkin M, Pfaar O, Pitsios C, Quirce S, Raap U, Raulf-Heimsoth M, Rhyner C, Robson-Ansley P, Alves RR, Roje Z, Rondon C, Rudzeviciene O, Ruëff F, Rukhadze M, Rumi G, Sackesen C, Santos AF, Santucci A, Scharf C, Schmidt-Weber C, Schnyder B, Schwarze J, Senna G, Sergejeva S, Seys S, Siracusa A, Skypala I, Sokolowska M, Spertini F, Spiewak R, Sprikkelman A, Sturm G, Swoboda I, Terreehorst I, Toskala E, Traidl-Hoffmann C, Venter C, Vlieg-Boerstra B, Whitacker P, Worm M, Xepapadaki P, Akdis CA. Research needs in allergy: an EAACI position paper, in collaboration with EFA. Clin Transl Allergy, 2012 Nov 2;2(1):21.

18. Syrigou E, Angelakopoulou A, Zande M, Panagiotou I, Roma E, Pitsios C. Allergy-test-driven elimination diet is useful in children with eosinophilic esophagitis, regardless of the severity of symptoms. Pediatr Allergy Immunol, 2015;26(4):323-9.

19. Makatsori M, Senna G, Pitsios C, Lleonart R, Klimek L, Nunes C, Rukhadze M, Rogala B, Gawlik R, Panzner P, Pfaar O, Calderon M. Prospective adherence to specific immunotherapy in Europe (PASTE) survey protocol. Clin Transl Allergy, 2015 Apr 27;5:17.

20. Pitsios C, Demoly P, Bilò MB, Gerth van Wijk R, Pfaar O, Sturm GJ, Rodriguez Del Rio P, Tsoumani M, Gawlik R, Paraskevopoulos G, Ruëff F, Valovirta E, Papadopoulos NG, Calderón MA. Clinical contraindications to allergen immunotherapy: an EAACI position paper. Allergy, 2015; 70(8): 897-909.

21. Pitsios C. Erythema multiforme caused by sildenafil in a HIV(+) subject. European Annals Allergy Clinical Immunology, 2016; 48:58-60.

22. Dhami S, Nurmatov U, Varga EM, Sturm G, Muraro A, Akdis CA, Antolín-Amérigo D, Bilò MB, Bokanovic D, Calderon MA, Cichocka-Jarosz E, Elberink JN, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Mosbech H, Pfaar O, Pitsios C, Pravettoni V, Roberts G, Ruëff F, Sin BA, Sheikh A. Allergen immunotherapy for insect venom allergy: protocol for a systemic review. Clin Transl Allergy, 2016; 6:6.

23. Dhami S, Nurmatov U, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Demoly P, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systemic review. Clin Transl Allergy, 2016; 6:12.

24. Dhami S, Zaman H, Varga EM, Sturm GJ, Muraro A, Akdis CA, Antolín-Amérigo D, Bilò MB, Bokanovic D, Calderon MA, Cichocka-Jarosz E, Oude Elberink JN, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Mosbech H, Ollert M, Pfaar O, Pitsios C, Pravettoni V, Roberts G, Ruëff F, Sin BA, Asaria M, Netuveli G, Sheikh A. Allergen immunotherapy for insect venom allergy: a systemic review and meta-analysis. Allergy, 2017; 72: 342-365.

25. Rodríguez Del Rio P, Pitsios C, Tsoumani M, Pfaar O, Paraskevopoulos G, Gawlik R, Valovirta E, Larenas-Linnemann D, Demoly P, Calderón MA. Physicians' experience and opinion on contraindications to allergen immunotherapy: The CONSIT survey. Ann Allergy Asthma Immunol, 2017; 118: 621-628.

26. Pitsios C, Lefoussis C, Dimitriou A, Giannakopoulos D, Ergazakis M, Vartholomaios S, Kouri M, Larenas-Linnemann D, Kompoti E. Allergen immunotherapy is safe during pollen season. Results of a 10-year, real-life prospective study. Revue Francaise d' Allergologie, 2017; 4: 302-307.

27. Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H, Agarwal A, Netuveli G Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina P, Mösges R, Elberink HO, Pajno G, Panwankar R, Pastorello E, Penagos M, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Schmidt-Weber C, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: a systemic review and meta-analysis. Allergy, 2017; Accepted, doi: 10.1111/all.13.

28. Nurmatov U, Dhami S, Arasi S, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin SY, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews. Clin Transl Allergy, 2017; 7: 24.

29. Sturm GJ, Varga EM, Roberts G, Mosbech H, Bilò MB, Akdis CA, Antolín-Amérigo D, Cichocka-Jarosz E, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Ollert M, Oude Elberink JNG, Pfaar O, Pitsios C, Pravettoni V, Ruëff F, Sin BA, Agache I, Angier E, Arasi S, Calderón MA, Fernandez-Rivas M, Halken S, Jutel M, Lau S, Pajno GB, van Ree R, Ryan D, Spranger O, van Wijk RG, Dhami S, Zaman H, Sheikh A, Muraro A. EAACI Guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy, 2017; doi: 10.1111/all.13262.

30. Iliopoulou A, Petrodimopoulou M, Konstantakopoulou M, Pasioti M, Papadopoulou A, Mikos N, Kompoti E, Korakianitis I, Kontogianni M, Pitsios C. Profilin sensitization and its clinical relevance to a population of atopic adults in Greece. Revue Française d'Allergologie, 2018; doi: 10.1016/j.reval.2017.11.001.

31. Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, Halken S, Larenas-Linnemann D, Pawankar R, Pitsios C, Sheikh A, Worm M, Arasi S, Calderon MA, Cingi C, Dhami S, Fauquert JL, Hamelmann E, Hellings P, Jacobsen L, Knol EF, Lin SY, Maggina P, Mösges R, Oude Elberink JNG, Pajno GB, Pastorello EA, Penagos M, Rotiroti G, Schmidt-Weber CB, Timmermans F, Tsilochristou O, Varga EM, Wilkinson JN, Williams A, Zhang L, Agache I, Angier E, Fernandez-Rivas M, Jutel M, Lau S, van Ree R, Ryan D, Sturm GJ, Muraro A. EAACI Guidelines on allergen immunotherapy: Allergic rhinoconjunctivitis. Allergy, 2017;00: 1-33. doi: 10.1111/all.13317

 

Profile Information

  • Medicine Diploma, University of Rome “La Sapienza”, Italy (1986-1992). 
  • Fellowship in Internal Medicine/ Thoracic Medicine, Thoracic Clinic, 251 General Air Force Hospital, Athens (1994)
  • Fellowship in Pediatrics, 2nd Paediatric Clinic, Penteli’s Children Hospital, Athens (1997-1999)                                            
  • Residency in Allergy, Allergology Dept., ‘Laikon’ General Hospital of Athens (2001-2004)
  •  Visiting Senior resident and visiting doctor, Mount Sinai School of Medicine, NY, USA (2003, 2005)
  • PhD in Immunology, School of Medicine, “Kapodistrakon” University of Athens. Thesis: “Study of the activation antigen CD69 in the various HIV-1 infection stages. Relation with T cell subpopulations (CD4, CD8, CD28) and functional tests.

 

TEACHING EXPERIENCE

Visiting Speaker, School of Nurses’ Specialization in Internal Medicine (2005).

Associate Teaching Faculty Member, Harokopio University of Athens (2009-2016). Teaching: 

  • “Pathophysiology ΙΙ”, for students of the 5th Semester
  • “Nutrition & Immunity”, elective of 7th Semester.
  • “Special topics of adults’ clinical nutrition”, for MSc degree students

Tutoring an MSc student of Harokopio University. Thesis: “Study on profilin sensitization in atopic patients and its implication in Oral Allergy Syndrome”

 

MEMBER OF SCIENTIFIC-PROFESSIONAL GROUPS         

  • Elected Member and Webmaster of the “Immunotherapy Interest Group”, European Academy of    Allergy & Clinical Immunology” (EAACI) (2011-2019)
  • Coordinator of “Contraindications in Immunotherapy” Task Force, EAACI (managing a grant of 15,000 euros) (2013-2014)
  • Chairmain of the Food Allergy Interest Group, Hellenic Society of Allergology & Clinical Immunology (2011-today)
  • Secretary Special of the Hellenic Society of Allergology & Clinical Immunology (2011-2015)
  • Treasurer of the Hellenic Union of Allergologists (2010-2012)
JOURNALS
  • Associate Editor of the journal “Hellenic Allergology and Clinical Immunology”
  • Reviewer of journals such as: Annals Allergy Clinical Immunology, Clinical Translational Allergy, Pediatric Allergy & Immunology, Clinical and Molecular Allergy, Journal of Molecular Evolution, Journal of Medical Case Reports

 

AWARDS                           

  • Study “Is bee-pollen safe for the atopic patient?” 5th Hellenic Congress of Allergology & Cl. Immunology, 3-5/4/2003, Athens, Greece.
  • Poster presentation: “Using AIT despite Contraindications; CONtraindications to Specific ImmunoTherapy (CONSIT) study”. EAACI Allergy School, Athens, Greece 11-13/9/2014
  • 2nd award for the “Study of IgE-sensitization to profilin and its relation with oral allergy syndrome” 11th Panhellenic Congress of Allergology & Cl. Immunology, 14-17/4/2016, Athens, Greece.  
  • 3nd award for the “Is reducing the maintenance dose of Immunotherapy to pollen during pollen season, necessary? Results of a 10-year-long prospective study” 11th Panhellenic Congress of Allergology & Cl. Immunology, 14-17/4/2016, Athens, Greece.  
  • Poster presentation: "Protocol of the PARC (Prevention of Allergic Rhinitis in Cyprus) program", 13rd Panhellenic Congress of Allergology & Cl. Immunology, 11-14/4/2019, Thessaloniki, Greece.

-National Coordinator (Greece) of the European PASTE study, regarding patients' adherence to allergen Immunotherapy. The study has been the outcome of an EAACI (European Academy of Allergy & Clinical Immunology) Task Force and has partially been completed.

-Member of the Task Force of EAACI: "Awareness and practice of allergen immunotherapy in primary care in Europe"

-Member of the Task Force of EAACI: "Food reintroduction in Eosinophilic Esophagitis".

-Co-ordinator of a meta-analysis regarding "The use of skin tests for the diagnosis of Eosinophilic Esophagitis"

-Study of profilin as allergen causing Oral Allergy Syndrome (OAS). A study on OAS prevalence in Greek population has been completed and results have been published. The presence of profilin in skin prick test extracts of pollen and fruits, using the SDS-PAGE method, have also been published. Study of OAS and profilin sensitization is going to be exended to Cypriot population.

-Program of Prevention of Allergic Rhinitis in Cyprus: The task of this program is to define the prevalence of allergic rhinitis in Cyprus. Initially interviews with the use of a questionnare are made, detecting the partecipants that have symptoms of rhinitis. Diagnosis of allergic rhinitis is set with a clinical examination and the use of skin-prick tests. The program is addressed to young adults who are students of UCY. Allergological advices are offered to the ones diagnosed as allergic, in order to prevent deterioration and progression of allergic rhinitis to asthma.

1. Pitsios C, Vithoulka A, Roumana A, Kompoti E, Kontou-Fili K. Multiple Physical Urticarias: Report of Three Cases and Review of the Literature. Allergy and Asthma Proceedings, 2003; Vol 24, 5:313-317.

2. Pitsios C, Papadopoulos D, Kompoti E, Manoussakis E, Garris V, Petalas K, Tassios I, Baibas N, Kontou-Fili K, Saxoni-Papageorgiou P, Papadopoulos NG. Efficacy and safety of mometasone furoate vs nedocromil sodium as prophylactic treatment for moderate/severe seasonal allergic rhinitis. Annals of Allergy, Asthma and Immunology, 2006; 96, 5:673-678.

3. Vythoulka A, Pitsios C, Kompoti E. Allergic reactions due to mizolastine. Annals of Allergy, Asthma and Immunology, 2006; 97, 2:262-263.

4. Stratopoulos C, Pitsios C, Valenti P, Anaglostopoulos G, Kotronis E. Medical Image. Deep vein thrombosis due to absence of inferior vena cava. N J Med J, 2006; 119:U2288.

5. Pitsios C, Chliva C, Mikos N, Kompoti E, Nowak-Wegrzyn A, Kontou-Fili K. Bee pollen sensitivity in airborne pollen allergic individuals. Annals of Allergy, Asthma and Immunology, 2006; 97:703-706.

6. Vartholomaios S, Pitsios C, Mikos N, Kompoti E, Kouridakis S. Allergy to Basil; a Lamiaceae herb. J Inv Allergy Clin Immunol, 2007; 17: 345-349.

7. Pitsios C, Dimitrakopoulou A, Tsalimalma K, Kordossis T, Choremi-Papadopoulou H. Expression of CD69 on T-cell subsets in HIV-1 disease. Scand J Clin Lab Invest, 2008; 68: 233-241.

8. Stefanaki E, Pitsios C. Occupational dermatitis due to carnation. Contact Dermat, 2008; 58: 119-120.

9. Pitsios C, Ergazakis M, Vartholomaios S, Kompoti E, Kontou-Fili K. Honey hypersensitivity in two atopic patients. Allergy Hypersensitivity Asthma, 2008: 17-20.

10. Roumana A, Pitsios C, Vartholomaios S, Kompoti E, Kontou-Fili K. The safety of initiating Hymenoptera immunotherapy at 1 microg of venom extract. J Allergy Clin Immunol, 2009; 124:379-81.

11. Pitsios C, Dimitriou A, Stefanaki EC, Kontou-Fili K. Anaphylaxis during skin testing with food allergens in children. Eur J Pediatr, 2009; 169: 613-615.

12. Pitsios C, Stefanaki EC, Helbling A. Type IV delayed-type hypersensitivity of the respiratory tract due to budesonide use: report of two cases and a literature review. Prim Care Respir J, 2010; 19:185-188.

13. Pitsios C, Dimitriou A, Kontou-Fili K. Allergic reactions during allergy skin testing with food allergens. Εur Ann Allergy Clin Immunol, 2009; 41: 126-8.

14. Pitsios C. Generalized allergic reactions during skin testing. Pediatr Allergy Immunol, 2010; 21: 557.

15. Pitsios C, Del Giacco S, Grigoreas C. Is free running screening test still useful? West Indian Med J, 2010; 59: 287-290.

16. Syrigou E, Pitsios C, Panagiotou I, Chouliaras G, Kitsiou S, Kanariou M, Roma-Giannikou E. Food allergy-related paediatric constipation: the usefulness of atopy patch test. Eur J Pediatr, 2011; 170: 1173-1178.

17. Papadopoulos NG, Agache I, Bavbek S, Bilo BM, Braido F, Cardona V, Custovic A, Demonchy J, Demoly P, Eigenmann P, Gayraud J, Grattan C, Heffler E, Hellings PW, Jutel M, Knol E, Lötvall J, Muraro A, Poulsen LK, Roberts G, Schmid-Grendelmeier P, Skevaki C, Triggiani M, Vanree R, Werfel T, Flood B, Palkonen S, Savli R, Allegri P, Annesi-Maesano I, Annunziato F, Antolin-Amerigo D, Apfelbacher C, Blanca M, Bogacka E, Bonadonna P, Bonini M, Boyman O, Brockow K, Burney P, Buters J, Butiene I, Calderon M, Cardell LO, Caubet JC, Celenk S, Cichocka-Jarosz E, Cingi C, Couto M, Dejong N, Del Giacco S, Douladiris N, Fassio F, Fauquert JL, Fernandez J, Rivas MF, Ferrer M, Flohr C, Gardner J, Genuneit J, Gevaert P, Groblewska A, Hamelmann E, Hoffmann HJ, Hoffmann-Sommergruber K, Hovhannisyan L, Hox V, Jahnsen FL, Kalayci O, Kalpaklioglu AF, Kleine-Tebbe J, Konstantinou G, Kurowski M, Lau S, Lauener R, Lauerma A, Logan K, Magnan A, Makowska J, Makrinioti H, Mangina P, Manole F, Mari A, Mazon A, Mills C, Mingomataj E, Niggemann B, Nilsson G, Ollert M, O'Mahony L, O'Neil S, Pala G, Papi A, Passalacqua G, Perkin M, Pfaar O, Pitsios C, Quirce S, Raap U, Raulf-Heimsoth M, Rhyner C, Robson-Ansley P, Alves RR, Roje Z, Rondon C, Rudzeviciene O, Ruëff F, Rukhadze M, Rumi G, Sackesen C, Santos AF, Santucci A, Scharf C, Schmidt-Weber C, Schnyder B, Schwarze J, Senna G, Sergejeva S, Seys S, Siracusa A, Skypala I, Sokolowska M, Spertini F, Spiewak R, Sprikkelman A, Sturm G, Swoboda I, Terreehorst I, Toskala E, Traidl-Hoffmann C, Venter C, Vlieg-Boerstra B, Whitacker P, Worm M, Xepapadaki P, Akdis CA. Research needs in allergy: an EAACI position paper, in collaboration with EFA. Clin Transl Allergy, 2012 Nov 2;2(1):21.

18. Syrigou E, Angelakopoulou A, Zande M, Panagiotou I, Roma E, Pitsios C. Allergy-test-driven elimination diet is useful in children with eosinophilic esophagitis, regardless of the severity of symptoms. Pediatr Allergy Immunol, 2015;26(4):323-9.

19. Makatsori M, Senna G, Pitsios C, Lleonart R, Klimek L, Nunes C, Rukhadze M, Rogala B, Gawlik R, Panzner P, Pfaar O, Calderon M. Prospective adherence to specific immunotherapy in Europe (PASTE) survey protocol. Clin Transl Allergy, 2015 Apr 27;5:17.

20. Pitsios C, Demoly P, Bilò MB, Gerth van Wijk R, Pfaar O, Sturm GJ, Rodriguez Del Rio P, Tsoumani M, Gawlik R, Paraskevopoulos G, Ruëff F, Valovirta E, Papadopoulos NG, Calderón MA. Clinical contraindications to allergen immunotherapy: an EAACI position paper. Allergy, 2015; 70(8): 897-909.

21. Pitsios C. Erythema multiforme caused by sildenafil in a HIV(+) subject. European Annals Allergy Clinical Immunology, 2016; 48:58-60.

22. Dhami S, Nurmatov U, Varga EM, Sturm G, Muraro A, Akdis CA, Antolín-Amérigo D, Bilò MB, Bokanovic D, Calderon MA, Cichocka-Jarosz E, Elberink JN, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Mosbech H, Pfaar O, Pitsios C, Pravettoni V, Roberts G, Ruëff F, Sin BA, Sheikh A. Allergen immunotherapy for insect venom allergy: protocol for a systemic review. Clin Transl Allergy, 2016; 6:6.

23. Dhami S, Nurmatov U, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Demoly P, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systemic review. Clin Transl Allergy, 2016; 6:12.

24. Dhami S, Zaman H, Varga EM, Sturm GJ, Muraro A, Akdis CA, Antolín-Amérigo D, Bilò MB, Bokanovic D, Calderon MA, Cichocka-Jarosz E, Oude Elberink JN, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Mosbech H, Ollert M, Pfaar O, Pitsios C, Pravettoni V, Roberts G, Ruëff F, Sin BA, Asaria M, Netuveli G, Sheikh A. Allergen immunotherapy for insect venom allergy: a systemic review and meta-analysis. Allergy, 2017; 72: 342-365.

25. Rodríguez Del Rio P, Pitsios C, Tsoumani M, Pfaar O, Paraskevopoulos G, Gawlik R, Valovirta E, Larenas-Linnemann D, Demoly P, Calderón MA. Physicians' experience and opinion on contraindications to allergen immunotherapy: The CONSIT survey. Ann Allergy Asthma Immunol, 2017; 118: 621-628.

26. Pitsios C, Lefoussis C, Dimitriou A, Giannakopoulos D, Ergazakis M, Vartholomaios S, Kouri M, Larenas-Linnemann D, Kompoti E. Allergen immunotherapy is safe during pollen season. Results of a 10-year, real-life prospective study. Revue Francaise d' Allergologie, 2017; 4: 302-307.

27. Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H, Agarwal A, Netuveli G Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina P, Mösges R, Elberink HO, Pajno G, Panwankar R, Pastorello E, Penagos M, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Schmidt-Weber C, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: a systemic review and meta-analysis. Allergy, 2017; Accepted, doi: 10.1111/all.13.

28. Nurmatov U, Dhami S, Arasi S, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin SY, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews. Clin Transl Allergy, 2017; 7: 24.

29. Sturm GJ, Varga EM, Roberts G, Mosbech H, Bilò MB, Akdis CA, Antolín-Amérigo D, Cichocka-Jarosz E, Gawlik R, Jakob T, Kosnik M, Lange J, Mingomataj E, Mitsias DI, Ollert M, Oude Elberink JNG, Pfaar O, Pitsios C, Pravettoni V, Ruëff F, Sin BA, Agache I, Angier E, Arasi S, Calderón MA, Fernandez-Rivas M, Halken S, Jutel M, Lau S, Pajno GB, van Ree R, Ryan D, Spranger O, van Wijk RG, Dhami S, Zaman H, Sheikh A, Muraro A. EAACI Guidelines on allergen immunotherapy: Hymenoptera venom allergy. Allergy, 2018; 78: 744-764.

30. Iliopoulou A, Petrodimopoulou M, Konstantakopoulou M, Pasioti M, Papadopoulou A, Mikos N, Kompoti E, Korakianitis I, Kontogianni M, Pitsios C. Profilin sensitization and its clinical relevance to a population of atopic adults in Greece. Revue Française d'Allergologie, 2018; doi: 10.1016/j.reval.2017.11.001.

31. Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, Halken S, Larenas-Linnemann D, Pawankar R, Pitsios C, Sheikh A, Worm M, Arasi S, Calderon MA, Cingi C, Dhami S, Fauquert JL, Hamelmann E, Hellings P, Jacobsen L, Knol EF, Lin SY, Maggina P, Mösges R, Oude Elberink JNG, Pajno GB, Pastorello EA, Penagos M, Rotiroti G, Schmidt-Weber CB, Timmermans F, Tsilochristou O, Varga EM, Wilkinson JN, Williams A, Zhang L, Agache I, Angier E, Fernandez-Rivas M, Jutel M, Lau S, van Ree R, Ryan D, Sturm GJ, Muraro A. EAACI Guidelines on allergen immunotherapy: Allergic rhinoconjunctivitis. Allergy, 2017; 73: 765-798.

32. Konstantinou AE, Christaki E, Pitsios C. Dose of itraconazole 100mg to treat allergic bronchopulmonary aspergillosis (ABPA) related eosinophilia: a cae report. Hippokratia, 2017; 21: 144-146.

33. Kontou-Fili K, Pitsios C, Kompoti E, Giannakopoulos D, Kouridakis S. Safety and efficacy of a progressively prolonged mantenance interval of venom immunotherapy. Int Arch Allergy Immunol. 2018;176: 39-43.

34. Pitsios C, Iliopoulou A, Kontogianni M, Papagregoriou G. Detection of profilin in SPT extracts that are supposed to contain it. Allergol Immunopathol (Madr). 2019;47(1):12-15.

35. Pitsios C, Dietis N. Ways to increase adherence to allergen immunotherapy. Curr Med Res Opin. 2019;35(6):1027-1031.