ΧΡΥΣΟΥΛΑ ΠΙΤΣΟΥΛΗ
ΠΙΤΣΟΥΛΗ ΧΡΥΣΟΥΛΑ
PITSOULI CHRYSOULA
...
ΕΠΙΚΟΥΡΟΣ/Η ΚΑΘΗΓΗΤΗΣ/ΡΙΑ
Τμήμα Βιολογικών Επιστημών
ΘΕΕ 02 - Σχολή Θετικών και Εφαρμοσμένων Επιστημών
Πανεπιστημιούπολη
FST 02, B218
22893766
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-

Προσωπικό Προφίλ

Πτυχίο Βιολογίας (1998) Τμήμα Βιολογίας, Πανεπιστήμιο Κρήτης, Ηράκλειο
Μάστερ Μοριακής Βιολογίας & Βιοϊατρικής (2000) Τμήμα Βιολογίας, Πανεπιστήμιο Κρήτης και ΙΜΒΒ, Ηράκλειο
Διδακτορικό Μοριακής Βιολογίας & Βιοϊατρικής (2005) Τμήμα Βιολογίας, Πανεπιστήμιο Κρήτης και ΙΜΒΒ, Ηράκλειο
 
Μεταδιδακτορική Έρευνα (2005-2011) Τμήμα Γενετικής, Ιατρική Σχολή, Πανεπιστήμιο Χάρβαρντ, Βοστώνη
Επίκουρος Καθηγήτρια (2012- ) Τμήμα Βιολογικών Επιστημών, Πανεπιστήμιο Κύπρου, Λευκωσία
 
 
Σηματοδοτικοί μηχανισμοί που ρυθμίζουν την ανάπτυξη και την ομοιόσταση της Δροσόφιλας
1. Μονοπάτια διακυτταρικής σηματοδότησης που ρυθμίζουν την ανάπτυξη οργάνων που μεταφέρουν οξυγόνο
2. Μηχανισμοί αναδιαμόρφωσης των οργάνων που μεταφέρουν οξυγόνο κατά την εντερική φλεγμονή και καρκινογένεση
 
 
 Δημοσιεύσεις
  1. Pitsouli, C. and Perrimon, N. (2013). The homeobox transcription factor Cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling 6(263):ra12
  2. Bangi, E., Pitsouli, C., Rahme, L.G., Cagan, R. and Apidianakis, Y. (2012). Immune response to bacteria induces dissemination of Ras-activated Drosophila hindgut cells. EMBO Reports 13(6):569-76
  3. Pitsouli, C. and Perrimon, N. (2010). Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development 137(21): 3615-24
  4. Apidianakis, Y.*, Pitsouli, C.*, Perrimon, N. and Rahme, L.G. (2009). Synergy between Bacterial Infection and Genetic Predisposition in Intestinal Dysplasia. Proc Natl Acad Sci USA 106(49): 20883-8 *equal contribution
  5. Markstein, M., Pitsouli, C., Villalta, C., Celniker, S.E. and Perrimon, N. (2008). Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics 40(4): 476-83
  6. Vinegoni, C. *, Pitsouli, C. *, Razansky, D. *, Perrimon, N. and Ntziachristos, V. (2008). In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods 5(1): 45-7 *equal contribution
  7. Glittenberg, M., Pitsouli, C., Garvey, C., Delidakis, C. and Bray, S. (2006). Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis. EMBO J 25(20): 4697-706
  8. Pitsouli, C. and Delidakis, C. (2005). The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development 132(18): 4041-50
  9. Pavlopoulos, E. *, Pitsouli, C. *, Klueg, K.M., Muskavitch, M.A., Moschonas, N.K. and Delidakis, C. (2001). neuralized encodes a peripheral membrane protein involved in Delta signaling and endocytosis. Dev Cell 1(6): 807-16 *equal contribution
 
Ανασκοπήσεις
  1. Kux, K. and Pitsouli, C. (2013). Tissue communication in regenerative inflammation: lessons from the fly gut. Frontiers in Microbiology (in press)
  2. Perrimon, N., Pitsouli, C. and Shilo, B.N. (2012). Signalling mechanisms controlling cell fate and embryonic patterning. CSHL Press, Edited by: Lewis Cantley, Tony Hunter, Richard Sever, and Jeremy Thorner, Cold Spring Harb Perspect in Biol 2012;1:a005975
  3. Pitsouli, C., Apidianakis, Y. and Perrimon, N. (2009). Homeostasis in infected epithelia: stem cells take the lead. Cell Host Microbe 6(4):301-7
  4. Vinegoni, C., Razansky, D., Pitsouli, C., Perrimon, N., Ntziachristos, V. and Weissleder, R. (2009). Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp 30. pii: 1510. doi: 10.3791/1510
  5. Pitsouli, C. and Perrimon, N. (2008). Developmental Biology: Our Fly Cousins’ gut. Nature 454: 592-3

Profile Information

B.Sc. in Biology (1998) Department of Biology, University of Crete, Heraklion
M.Sc. in Molecular Biology & Biomedicine (2000) Department of Biology, University of Crete and IMBB, Heraklion
Ph.D. in Molecular Biology & Biomedicine (2005) Department of Biology, University of Crete and IMBB, Heraklion
 
Postdoctoral Research Fellow (2005-2011) Department of Genetics, Harvard Medical School, Boston
Assistant Professor (2012- ) Department of Biological Sciences, University of Cyprus, Nicosia
 
 
Development and homeostasis in Drosophila melanogaster
1. Identification of signaling pathways that control development of oxygen-transporting tubes
2. Remodeling of oxygen-transporting tubes during intestinal inflammation and cancer
 
 
Research Papers
  1. Pitsouli, C. and Perrimon, N. (2013). The homeobox transcription factor Cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling 6(263):ra12
  2. Bangi, E., Pitsouli, C., Rahme, L.G., Cagan, R. and Apidianakis, Y. (2012). Immune response to bacteria induces dissemination of Ras-activated Drosophila hindgut cells. EMBO Reports 13(6):569-76
  3. Pitsouli, C. and Perrimon, N. (2010). Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development 137(21): 3615-24
  4. Apidianakis, Y.*, Pitsouli, C.*, Perrimon, N. and Rahme, L.G. (2009). Synergy between Bacterial Infection and Genetic Predisposition in Intestinal Dysplasia. Proc Natl Acad Sci USA 106(49): 20883-8 *equal contribution
  5. Markstein, M., Pitsouli, C., Villalta, C., Celniker, S.E. and Perrimon, N. (2008). Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics 40(4): 476-83
  6. Vinegoni, C. *, Pitsouli, C. *, Razansky, D. *, Perrimon, N. and Ntziachristos, V. (2008). In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods 5(1): 45-7 *equal contribution
  7. Glittenberg, M., Pitsouli, C., Garvey, C., Delidakis, C. and Bray, S. (2006). Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis. EMBO J. 25(20): 4697-706
  8. Pitsouli, C. and Delidakis, C. (2005). The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development 132(18): 4041-50
  9. Pavlopoulos, E. *, Pitsouli, C. *, Klueg, K.M., Muskavitch, M.A., Moschonas, N.K. and Delidakis, C. (2001). neuralized encodes a peripheral membrane protein involved in Delta signaling and endocytosis. Dev Cell 1(6): 807-16 *equal contribution
 
Review Articles
  1. Kux, K. and Pitsouli, C. (2013). Tissue communication in regenerative inflammation: lessons from the fly gut. Frontiers in Microbiology (in press)
  2. Perrimon, N., Pitsouli, C. and Shilo, B.N. (2012). Signalling mechanisms controlling cell fate and embryonic patterning. CSHL Press, Edited by: Lewis Cantley, Tony Hunter, Richard Sever, and Jeremy Thorner, Cold Spring Harb Perspect in Biol 2012;1:a005975
  3. Pitsouli, C., Apidianakis, Y. and Perrimon, N. (2009). Homeostasis in infected epithelia: stem cells take the lead. Cell Host Microbe 6(4):301-7
  4. Vinegoni, C., Razansky, D., Pitsouli, C., Perrimon, N., Ntziachristos, V. and Weissleder, R. (2009). Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp30. pii: 1510. doi: 10.3791/1510
  5. Pitsouli, C. and Perrimon, N. (2008). Developmental Biology: Our Fly Cousins’ gut. Nature 454: 592-3