Selected list

  • Savva I, Pierides A, Deltas C. RAAS inhibition and the course of Alport syndrome. Pharmacol Res. 2016 Mar 16;107:205-210. PubMed Link
  • Voskarides K, Mazières S, Hadjipanagi D, Di Cristofaro J, Ignatiou A, Stefanou C, King RJ, Underhill PA, Chiaroni J, Deltas C. Y-chromosome phylogeographic analysis of the Greek-Cypriot population reveals elements consistent with Neolithic and Bronze Age settlements. Investig Genet. 2016 Feb 11;7:1. eCollection 2016. PubMed Link
  • Stefanou C, Pieri M, Savva I, Georgiou G, Pierides A, Voskarides K, Deltas C. Co-Inheritance of Functional Podocin Variants with Heterozygous Collagen IV Mutations Predisposes to Renal Failure. Nephron. 2015;130(3):200-12. PubMed Link

  • Eckardt KU, Alper SL, Antignac C, Bleyer AJ, Chauveau D, Dahan K, Deltas C, Hosking A, Kmoch S, Rampoldi L, Wiesener M, Wolf MT, Devuyst O. Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management-A KDIGO consensus report. Kidney Int. 2015 Oct;88(4):676-83. PubMed Link

  • Gross O, Perin L, Deltas C. Alport syndrome from bench to bedside: the potential of current treatment beyond RAAS-blockade and the horizon of future therapies. Nephrol Dial Transplant. 2014 Sep;29 Suppl 4:iv124-30. PubMed Link

  • The International Alport Mutation Consortium, Savige J, Ars E, Cotton RG, Crockett D, Dagher H, Deltas C, Ding J, Flinter F, Pont-Kingdon G, Smaoui N, Torra R, Storey H. DNA variant databases improve test accuracy and phenotype prediction in Alport syndrome. Pediatr Nephrol. 2014 Jun;29(6):971-7. PubMed Link

  • Bleyer AJ, Kmoch S, Antignac C, Robins V, Kidd K, Kelsoe JR, Hladik G, Klemmer P, Knohl SJ, Scheinman SJ, Vo N, Santi A, Harris A, Canaday O, Weller N, Hulick PJ, Vogel K, Rahbari-Oskoui FF, Tuazon J, Deltas C, Somers D, Megarbane A, Kimmel PL, Sperati CJ, Orr-Urtreger A, Ben-Shachar S, Waugh DA, McGinn S, Bleyer AJ Jr, Hodaňová K, Vyleťal P, Živná M, Hart TC, Hart PS. Variable clinical presentation of a MUC1 mutation causing medullary cystic kidney disease type 1. Clin J Am Soc Nephrol. 2014 Mar;9(3):527-35. PubMed Link

  • Zaravinos A, Pieri M, Mourmouras N, Anastasiadou N, Zouvani I, Delakas I, Deltas C. Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks. Oncoscience. 2014 Jan 3;1(2):117-31. PubMed Link

    *Figure 2 of the paper was chosen as a cover for the second issue of Oncoscience.

  • Papazachariou L, Demosthenous P, Pieri M, Papagregoriou G, Savva I, StavrouC, Zavros M, Athanasiou Y, Ioannou K, Patsias C, PanagidesA, Potamitis P, Demetriou K, Prikis M, Hadjigavriel M, KkolouM, Loukaidou P, Pastelli A, Michael A, LazarouA, Arsali M, Damianou L, Goutziamani I, Soloukides A, Yioukas L, Elia A, Zouvani I, Polycarpou P, Pierides A, Voskarides K, Deltas C. Frequency of COL4A3/COL4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response. Focal and segmental glomerulosclerosis is a frequent development during ageing. PLoS One. 2014 Dec 16;9(12):e115015. PubMed Link

  • Erguler K, Pieri P, Deltas C. A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery adaptation and apoptosis. BMC Syst Biol. 2013 Feb 21;7:16. PubMed Link

  • Deltas C, Pierides A, Voskarides K. Molecular genetics of familial hematuric diseases. Nephrol Dial Transplant. 2013 Dec;28(12):2946-2960. PubMed Link

  • Pieri Μ, Stefanou C, Zaravinos A, Erguler K, Stylianou C, Lapathitis G, Karaiskos C, Savva I, Paraskeva R, Dweep H, Sticht C, Anastasiadou N, Zouvani I, Goumenos D, Felekkis K, Saleem M, Voskarides K, Gretz N, Deltas C. Evidence for activation of the unfolded protein response in collagen IV nephropathies. J Am Soc Nephrol. 2014 Feb;25(2):260-75. PubMed Link

  • Zaravinos A, Lambrou GI, Mourmouras N, Katafygiotis P, Papagregoriou G, Giannikou K, Delakas D, Deltas C. New miRNA profiles accurately distinguish renal cell carcinomas and upper tract urothelial carcinomas from the normal kidney. PLoS One 2014 Mar 12;9(3):e91646. PubMed Link

  • Voskarides K, Demosthenous P, Papazachariou L, Arsali M, Athanasiou Y, Zavros M, Stylianou K, Xydakis D, Daphnis E, Gale DP, Maxwell PH, Elia A, Pattaro C, Pierides A, Deltas C. Epistatic Role of the MYH9/APOL1 Region on Familial Hematuria Genes. PLoS One 2013;8(3):e57925. PubMed Link

  • Deltas C, Gale D, Cook T, Voskarides K, Athanasiou Y, Pierides A. C3 Glomerulonephritis/CFHR5 Nephropathy Is an Endemic Disease in Cyprus: Clinical and Molecular Findings in 21 Families. Adv Exp Med Biol. 2013;735:189-96. PubMed Link

  • Deltas C, Voskarides K, Demosthenous P, Papazachariou L, Zirogiannis P, Pierides A. The power of molecular genetics in establishing the diagnosis and offering prenatal testing: The case for Alport Syndrome. Diseases of Renal Parenchyma (2012) ISBN: 978-953-51-0245-8. Link

  • Papagregoriou G, Erguler K, Dweep H, Voskarides K, Koupepidou P, Athanasiou Y, Pierides A, Gretz N, Felekkis KN, Deltas C. A miR-1207-5p Binding Site Polymorphism Abolishes Regulation of HBEGF and Is Associated with Disease Severity in CFHR5 Nephropathy. PLoS One 2012; 7(2):e31021. PubMed Link

  • Deltas C, Pierides A, Voskarides K. The role of molecular genetics in diagnosing familial hematuria(s). Pediatr Nephrol. 2012 Aug;27(8):1221-31. PubMed Link

  • Felekkis K, Voskarides K, Dweep H, Sticht C, Gretz N, Deltas C. Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction? Mol Biol Evol. 2011 Sep;28(9):2421-4. PubMed Link

  • Demosthenous P, Voskarides K, Stylianou K, Hadjigavriel M, Arsali M, Patsias C, Georgaki E, Zirogiannis P, Stavrou C, Daphnis E, Pierides A, Deltas C, the Hellenic Nephrogenetics Research Consortium. X-linked Alport syndrome in Hellenic families: Phenotypic heterogeneity and mutations near interruptions of the collagen domain in COL4A5. Clin Genet. 2012 Mar;81(3):240-8. PubMed Link

  • Athanasiou Y, Voskarides K, Gale DP, Damianou L, Patsias C, Zavros M, Maxwell PH, Cook HT, Demosthenous P, Hadjisavvas A, Kyriacou K, Zouvani I, Pierides A, Deltas C. Familial C3 Glomerulopathy Associated with CFHR5 Mutations: Clinical Characteristics of 91 Patients in 16 Pedigrees. ClinJ Am Soc Nephrol. 2011 Jun;6(6):1436-46. PubMed Link

  • Gale DP, de Jorge EG, Cook HT, Martinez-Barricarte R, Hadjisavvas A, McLean AG, Pusey CD, Pierides A, Kyriacou K, Athanasiou Y, Voskarides K, Deltas C, Palmer A, Frémeaux-Bacchi V, de Cordoba SR, Maxwell PH, Pickering MC. Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis. Lancet 2010 Sep 4;376(9743):794-801. Pubmed Link

  • Koupepidou P, Felekkis KN, Kränzlin B, Sticht C, Gretz N, Deltas C. Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways. BMC Nephrol. Sep 2;11:23. PubMed Link

  • Deltas C. Small and Big Countries and the Sharing of Expertise and Biological Samples Under a New Perspective. The Place for Biobanks and Core Facilities Austral-Asian. Journal of Cancer (2010) 9 135-136.

  • Liu M, Shi S, Senthilnathan S, Yu J, Wu E, Bergmann C, Zerres K, Bogdanova N, Coto E, Deltas C. Genetic Variation of DKK3 May Modify Renal Disease Severity in ADPKD. J Am Soc Nephrol. 2010 Sep;21 (9):1510-20. PubMed Link

  • Pierides A, Voskarides K, Athanasiou Y, Ioannou K, Damianou L, Arsali M, Zavros M, Pierides M, Vargemezis V, Patsias C, Zouvani I, Elia A, Kyriacou K, Deltas C. Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis. Nephrol Dial Transplant. 2009 Sep;24(9):2721-9. PubMed Link

  • Voskarides K, Deltas C. Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches. J Mol Diagn. 2009 Jul;11(4):311-8. PubMed Link

  • Deltas C. Thin basement membrane nephropathy: is there genetic predisposition to more severe disease? Pediatr Nephrol. 2009 Apr;24(4):877-9. PubMed Link

  • Voskarides K, Makariou C, Papagregoriou G, Stergiou N, Printza N, Alexopoulos E, Elia A, Papachristou F, Pierides A, Georgaki E, Deltas C. NPHS2 screening with SURVEYOR in Hellenic children with steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2008 Aug;23(8):1373-5. PubMed Link

  • Felekkis KN, Koupepidou P, Kastanos E, Witzgall R, Bai C, Li L, Tsiokas L, Gretz N, Deltas C. Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2. BMC Nephrol. 2008 Aug 25;9:10. PubMed Link

  • Voskarides K, Damianou L, Neocleous V, Zouvani I, Christodoulidou S, Hadjiconstantinou V, Ioannou K, Athanasiou Y, Patsias C, Alexopoulos E, Pierides A, Kyriacou K, Deltas C. COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy. J Am Soc Nephrol. 2007 Nov; 18(11):3004-16. PubMed Link

    It was featured in the Highlights of this issue while a special invited Editorial by CE Kashtan was published in the same issue commenting on the results. Also, this paper was included in the list of papers recommended for reading, by the Nephrology, Dialysis, Transplantation Journal, issue of November 2007.